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Article Dans Une Revue Chemistry - A European Journal Année : 2020

Pd‐Catalyzed Directed Thiocyanation Reaction by C−H Bond Activation

Résumé

The Pd-catalyzed directed thiocyanation reaction of arenes and heteroarenes by CÀHb ond activation was achieved. In the presence of an electrophilic SCN source, this original methodology offered an efficient tool to access ap anel of functionalized thiocyanated compounds (21 examples, up to 78 %yield). Post-functionalization reactions further demonstrated the synthetic utility of the approach by converting the SCN-containing molecules into value-added scaffolds.

Domaines

Chimie organique
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Dates et versions

hal-03004678 , version 1 (07-12-2020)

Identifiants

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Mélissa Gao, Mu-Yi Chen, Xavier Pannecoucke, Philippe Jubault, Tatiana Besset. Pd‐Catalyzed Directed Thiocyanation Reaction by C−H Bond Activation. Chemistry - A European Journal, 2020, 22 (19), pp.7556-7561. ⟨10.1002/chem.202003521⟩. ⟨hal-03004678⟩
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