Controlled Dimroth Rearrangement in the Suzuki-Miyaura Cross Coupling of Triazolopyridopyrimidines. - ANR - Agence nationale de la recherche Accéder directement au contenu
Article Dans Une Revue Journal of Organic Chemistry Année : 2016

Controlled Dimroth Rearrangement in the Suzuki-Miyaura Cross Coupling of Triazolopyridopyrimidines.

Résumé

Polynitrogen heterocycles are often subject to Dimroth rearrangement which consists of ring opening, bond rotation, and ring closure. In this note, we report a synthesis of two new families of triazolopyridopyrimidines. Successful functionalization via a Suzuki-Miyaura coupling was performed with total control of triazole (Dimroth) isomerization based on the judicious choice of reaction conditions.

Domaines

Matériaux
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Dates et versions

hal-01432873 , version 1 (12-01-2017)

Identifiants

Citer

Anthony Champiré, Christine Vala, Achraf Laabid, Ahmed Benharref, Mathieu Marchivie, et al.. Controlled Dimroth Rearrangement in the Suzuki-Miyaura Cross Coupling of Triazolopyridopyrimidines.. Journal of Organic Chemistry, 2016, 81 (24), pp.12506-12513. ⟨10.1021/acs.joc.6b02357⟩. ⟨hal-01432873⟩
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