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Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers

Luis Molinos-Albert , Valerie Lorin , Valérie Monceaux , Sylvie Orr , Asma Essat , et al.
Nature Communications, 2022, 13 (1), pp.1944. ⟨10.1038/s41467-022-29511-1⟩
Article dans une revue pasteur-03654232v1
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Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Delphine Planas , Isabelle Staropoli , Vincent Michel , Frederic Lemoine , Flora Donati , et al.
Nature Communications, 2024, 15 (1), pp.2254. ⟨10.1038/s41467-024-46490-7⟩
Article dans une revue pasteur-04530809v1
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TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice

Véronique Godot , Colas Tcherakian , Laurine Gil , Iñaki Cervera-Marzal , Guangming Li , et al.
PLoS Pathogens, 2020, 16, ⟨10.1371/journal.ppat.1009025⟩
Article dans une revue hal-04296375v1
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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
Nature Immunology, 2021, ⟨10.1038/s41590-021-01028-7⟩
Article dans une revue pasteur-03384279v1
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Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

Valérie Lorin , Anne Danckaert , Françoise Porrot , Olivier Schwartz , Philippe Afonso , et al.
mBio, 2020, 11 (5), pp.e02424-20. ⟨10.1128/mBio.02424-20⟩
Article dans une revue pasteur-03246667v1
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High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1

William Bolland , Vincent Michel , Delphine Planas , Mathieu Hubert , Isabelle Staropoli , et al.
Journal of Virology, 2024, 98 (1), pp.e0135123. ⟨10.1128/jvi.01351-23⟩
Article dans une revue pasteur-04369613v1
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Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies

Timothée Bruel , Karl Stéfic , Yann Nguyen , Donatella Toniutti , Isabelle Staropoli , et al.
Cell Reports Medicine, 2022, 3 (12), pp.100850. ⟨10.1016/j.xcrm.2022.100850⟩
Article dans une revue pasteur-04165260v1
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Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

Jonathan Torres , Gabriel Ozorowski , Emanuele Andreano , Hejun Liu , Jeffrey Copps , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (20), pp.e2120976119. ⟨10.1073/pnas.2120976119⟩
Article dans une revue pasteur-04082754v1
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Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells

Caroline Passaes , Delphine Desjardins , Anaïs Chapel , Valérie Monceaux , Julien Lemaitre , et al.
Nature Communications, 2024, 15 (1), pp.178. ⟨10.1038/s41467-023-44389-3⟩
Article dans une revue pasteur-04598798v2
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A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

Ludivine Grzelak , Sarah Temmam , Cyril Planchais , Caroline Demeret , Laura Tondeur , et al.
Science Translational Medicine, 2020, 12 (559), pp.eabc3103. ⟨10.1126/scitranslmed.abc3103⟩
Article dans une revue pasteur-03139185v1

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

Luis M Molinos-Albert , Eduard Baquero , Mélanie Bouvin-Pley , Valerie Lorin , Caroline Charre , et al.
Cell Host & Microbe, 2023, 31 (8), pp.1275-1287.e8. ⟨10.1016/j.chom.2023.06.006⟩
Article dans une revue pasteur-04168501v1
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Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Cyril Planchais , Remi Noe , Marie Gilbert , Maxime Lecerf , Srini V Kaveri , et al.
Communications Biology, 2023, 6, pp.168. ⟨10.1038/s42003-023-04535-5⟩
Article dans une revue hal-03988037v1
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Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

Valerie Lorin , Ignacio Fernández , Guillemette Masse-Ranson , Mélanie Bouvin-Pley , Luis M. Molinos-Albert , et al.
Journal of Experimental Medicine, 2022, 219 (3), pp.e20212045. ⟨10.1084/jem.20212045⟩
Article dans une revue pasteur-03654254v1
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Tocilizumab-treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants

Camille Chauvin , Laurine Levillayer , Mathilde Roumier , Hubert Nielly , Claude Roth , et al.
iScience, 2023, 26 (3), pp.106124. ⟨10.1016/j.isci.2023.106124⟩
Article dans une revue hal-04090334v1
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Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Jérémy Dufloo , Cyril Planchais , Stéphane Frémont , Valerie Lorin , Florence Guivel-Benhassine , et al.
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Article dans une revue pasteur-03654220v1
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Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis

Marie Armani-Tourret , Zhicheng Zhou , Romain Gasser , Isabelle Staropoli , Vincent Cantaloube-Ferrieu , et al.
PLoS Pathogens, 2021, 17 (4), pp.e1009526. ⟨10.1371/journal.ppat.1009526⟩
Article dans une revue hal-03204143v1
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Variants with the N501Y mutation extend SARS-CoV-2 host range to mice, with contact transmission

Xavier Montagutelli , Matthieu Prot , Laurine Levillayer , Eduard Baquero Salazar , Grégory Jouvion , et al.
2023
Pré-publication, Document de travail pasteur-04168583v1
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Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

Min-Wen Ku , Maryline Bourgine , Pierre Authié , Jodie Lopez , Kirill Nemirov , et al.
Cell Host & Microbe, 2020, ⟨10.1016/j.chom.2020.12.010⟩
Article dans une revue pasteur-03108682v1

IRF8 regulates efficacy of therapeutic anti‐CD20 monoclonal antibodies

Ludivine Grzelak , Ferdinand Roesch , Amaury Vaysse , Anne Biton , Rachel Legendre , et al.
European Journal of Immunology, 2022, 52 (10), pp.1648-1661. ⟨10.1002/eji.202250037⟩
Article dans une revue hal-03833626v1
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SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells

Nicolas Huot , Cyril Planchais , Pierre Rosenbaum , Vanessa Contreras , Beatrice Jacquelin , et al.
Nature Immunology, 2023, 24 (12), pp.2068-2079. ⟨10.1038/s41590-023-01661-4⟩
Article dans une revue hal-04597995v1

Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5

Isabelle Staropoli , Jérémy Dufloo , Anaïs Ducher , Pierre-Henri Commère , Anna Sartori-Rupp , et al.
Journal of Virology, 2020, 94 (6), ⟨10.1128/JVI.01783-19⟩
Article dans une revue pasteur-02561978v1

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

Delphine Planas , Nell Saunders , Piet Maes , Florence Guivel-Benhassine , Cyril Planchais , et al.
Nature, 2022, 602 (7898), pp.671-675. ⟨10.1038/s41586-021-04389-z⟩
Article dans une revue pasteur-03654259v1
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Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers

Verena Hehle , Maxime Beretta , M Bourgine , Malika Ait-Goughoulte , Cyril Planchais , et al.
Journal of Experimental Medicine, 2020, 217 (10), pp.e20200840. ⟨10.1084/jem.20200840⟩
Article dans une revue pasteur-03242779v1
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A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis

Camille de Cevins , Marine Luka , Nikaïa Smith , Sonia Meynier , Aude Magérus , et al.
Med, 2021, 2 (9), pp.1072-1092.e7. ⟨10.1016/j.medj.2021.08.002⟩
Article dans une revue hal-03590894v1
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Easy pan-detection of human IgA immunoglobulins

Cyril Planchais , Hugo Mouquet
Journal of Immunological Methods, 2020, 484-485, pp.112833. ⟨10.1016/j.jim.2020.112833⟩
Article dans une revue hal-03491579v1
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Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies

Jérémy Dufloo , Ludivine Grzelak , Isabelle Staropoli , Yoann Madec , Laura Tondeur , et al.
Cell Reports Medicine, 2021, 2 (5), pp.100275. ⟨10.1016/j.xcrm.2021.100275⟩
Article dans une revue pasteur-03229805v1
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Escape of SARS-CoV-2 Variants KP.1.1, LB.1, and KP.3.3 From Approved Monoclonal Antibodies

Delphine Planas , Isabelle Staropoli , Cyril Planchais , Emilie Yab , Banujaa Jeyarajah , et al.
Pathogens and Immunity, 2024, 10 (1), pp.1-11. ⟨10.20411/pai.v10i1.752⟩
Article dans une revue pasteur-04748459v1

Binding mechanisms of therapeutic antibodies to human CD20

Anand Kumar , Cyril Planchais , Rémi Fronzes , Hugo Mouquet , Nicolas Reyes
Science, 2020, 369 (6505), pp.793-799. ⟨10.1126/science.abb8008⟩
Article dans une revue hal-03418565v1
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Distinct systemic and mucosal immune responses to SARS-CoV-2

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
2021
Pré-publication, Document de travail pasteur-03244398v1
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HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

Cyril Planchais , Ayrin Kök , Alexia Kanyavuz , Valérie Lorin , Timothée Bruel , et al.
Cell Reports, 2019, 27 (2), pp.572-585.e7. ⟨10.1016/j.celrep.2019.03.032⟩
Article dans une revue hal-02102470v1