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Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics

Matteo Broketa , Aurélien Sokal , Michael Mor , Pablo Canales-Herrerias , Angga Perima , et al.
JCI Insight, 2023, In press. ⟨10.1172/jci.insight.166602⟩
Article dans une revue pasteur-04111772v1
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Single-Cell Technologies for the Study of Antibody-Secreting Cells

Matteo Broketa , Pierre Bruhns
Frontiers in Immunology, 2022, 12, pp.821729. ⟨10.3389/fimmu.2021.821729⟩
Article dans une revue hal-03582460v1
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Mouse Models and Tools for the in vivo Study of Neutrophils

Julien Stackowicz , Friederike Jönsson , Laurent L. Reber
Frontiers in Immunology, 2020, 10, pp.3130. ⟨10.3389/fimmu.2019.03130⟩
Article dans une revue pasteur-02447221v1
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Deep phenotypic characterization of immunization-induced antibacterial IgG repertoires in mice using a single-antibody bioassay

Millie Heo , Guilhem Chenon , Carlos Castrillon , Jérôme Bibette , Pierre Bruhns , et al.
Communications Biology, 2020, 3 (1), pp.614. ⟨10.1038/s42003-020-01296-3⟩
Article dans une revue hal-03054253v1
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Deep learning enabled label-free microfluidic droplet classification for single cell functional assays

Thibault Vanhoucke , Angga Perima , Lorenzo Zolfanelli , Pierre Bruhns , Matteo Broketa
Frontiers in Bioengineering and Biotechnology, 2024, 12, pp.1468738. ⟨10.3389/fbioe.2024.1468738⟩
Article dans une revue pasteur-04703977v1
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Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice

Eva Conde , Romain Bertrand , Bianca Balbino , Jonathan Bonnefoy , Julien Stackowicz , et al.
Nature Communications, 2021, 12 (1), pp.2574. ⟨10.1038/s41467-021-22834-5⟩
Article dans une revue hal-03229636v1

Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring

Klaus Eyer , Raphaël C L Doineau , Carlos E Castrillon , Luis Briseño-Roa , Vera Menrath , et al.
Nature Biotechnology, 2017, 35 (10), pp.977 - 982. ⟨10.1038/nbt.3964⟩
Article dans une revue hal-01639647v1

Anti-S-layer monoclonal antibodies impact C. difficile physiology

Lise Hunault , Emile Auria , Patrick England , Julien Deschamps , Romain Briandet , et al.
2023
Pré-publication, Document de travail hal-04271946v1
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IgA dominates the early neutralizing antibody response to SARS-CoV-2

Delphine Sterlin , Alexis Mathian , Makoto Miyara , Audrey Mohr , François Anna , et al.
Science Translational Medicine, 2020, pp.eabd2223. ⟨10.1126/scitranslmed.abd2223⟩
Article dans une revue hal-03105620v1
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Pharmacological approaches to target type 2 cytokines in asthma

Laurent Guilleminault , Eva Conde , Laurent Reber
Pharmacology and Therapeutics, 2022, 237, pp.108167. ⟨10.1016/j.pharmthera.2022.108167⟩
Article dans une revue hal-03988416v1
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The anti‐FcεRI antibody MAR‐1 depletes basophils and cross‐reacts with myeloid cells through its Fc portion

William Worrall , Jasper Kamphuis , Julien Stackowicz , Aurélie Mougel , Emilie Mauré , et al.
Allergy, 2022, 77 (6), pp.1903-1906. ⟨10.1111/all.15269⟩
Article dans une revue hal-03987932v1
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Systemic anti-commensal response to fungi analyzed by flow cytometry is related to gut mycobiome ecology

Alicia Moreno-Sabater , Gaëlle Autaa , Delphine Sterlin , Amenie Jerbi , Remy Villette , et al.
Microbiome, 2020, 8 (1), pp.159. ⟨10.1186/s40168-020-00924-8⟩
Article dans une revue hal-03071667v1
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A monoclonal antibody collection for C. difficile typing ?

Lise Hunault , Patrick England , Frédéric Barbut , Bruno Iannascoli , Ophélie Godon , et al.
Gut Pathogens, 2024, 16 (1), pp.4. ⟨10.1186/s13099-023-00592-7⟩
Article dans une revue hal-04441824v2
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Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

Stéphane Marot , Isabelle Malet , Valentin Leducq , Karen Zafilaza , Delphine Sterlin , et al.
Nature Communications, 2021, 12 (1), pp.844. ⟨10.1038/s41467-021-21111-9⟩
Article dans une revue hal-03138467v1

Development and preclinical evaluation of a vaccine targeting IL‐4 and IL‐13 for the treatment of allergic asthma

Eva Conde , Pierre Bruhns , Vincent Serra , Laurent Reber
Allergy, 2021, 76 (11), pp.3553-3555. ⟨10.1111/all.14998⟩
Article dans une revue hal-03779481v1
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Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a+ CD4+ T Cells From Early HIV Infection to Effective cART

Sixtine Coindre , Nicolas Tchitchek , Lamine Alaoui , Bruno Vaslin , Christine Bourgeois , et al.
Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.01217⟩
Article dans une revue hal-02386113v1
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Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection

Sixtine Coindre , Nicolas Tchitchek , Lamine Alaoui , Bruno Vaslin , Christine Bourgeois , et al.
Frontiers in Immunology, 2019, ⟨10.3389/fimmu.2019.02677⟩
Article dans une revue hal-02386129v1
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Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome

Julien Stackowicz , Nicolas Gaudenzio , Nadine Serhan , Eva Conde , Ophélie Godon , et al.
Journal of Experimental Medicine, 2021, 218 (10), pp.e20201466. ⟨10.1084/jem.20201466⟩
Article dans une revue hal-03663419v1

Cutting Edge: Neutralizing Public Antibody Responses Are an Ancient Form of Defense Conserved in Fish and Mammals

Rosario Castro , Sofie Navelsaker , Bertrand Collet , Luc Jouneau , Pascal Bochet , et al.
Journal of Immunology, 2021, 207 (2), pp.371-375. ⟨10.4049/jimmunol.2100149⟩
Article dans une revue hal-03327860v1
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Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models

Alice Dejoux , Qianqian Zhu , Christelle Ganneau , Odile Richard-Le Goff , Ophélie Godon , et al.
Science Translational Medicine, 2024, 16 (764), pp.eado4463. ⟨10.1126/scitranslmed.ado4463⟩
Article dans une revue pasteur-04706288v1
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Standardized high‐dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies

Tom Dott , Slobodan Culina , Rene Chemali , Cedric Ait Mansour , Florian Dubois , et al.
Cytometry Part A, 2024, 105 (2), pp.124-138. ⟨10.1002/cyto.a.24801⟩
Article dans une revue pasteur-04221005v1
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Isolation methods determine human neutrophil responses after stimulation

Vanessa Krémer , Ophélie Godon , Pierre Bruhns , Friederike Jönsson , Luc de Chaisemartin
Frontiers in Immunology, 2023, 14, pp.1301183. ⟨10.3389/fimmu.2023.1301183⟩
Article dans une revue pasteur-04738760v1
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Human IgA binds a diverse array of commensal bacteria

Delphine Sterlin , Jehane Fadlallah , Olivia Adams , Claire Fieschi , Christophe Parizot , et al.
Journal of Experimental Medicine, 2020, 217 (3), pp.e20181635. ⟨10.1084/jem.20181635⟩
Article dans une revue hal-02433421v1
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The role of IgG subclasses and platelets in experimental anaphylaxis

Ophélie Godon , Béatrice Hechler , Friederike Jönsson
Journal of Allergy and Clinical Immunology, 2021, ⟨10.1016/j.jaci.2021.01.009⟩
Article dans une revue pasteur-03153702v1
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The anti-IgE mAb Omalizumab induces adverse reactions by engaging Fcγ receptors

Bianca Balbino , Pauline Herviou , Ophélie Godon , Julien Stackowicz , Odile Richard-Le Goff , et al.
Journal of Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
Article dans une revue pasteur-02451133v1
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Intravenous immunoglobulin induces IL-4 in human basophils by signaling through 1 surface-bound IgE

Caroline C Galeotti , Emmanuel Stephen-Victor , Anupama Karnam , Mrinmoy Das , Laurent Gilardin , et al.
Journal of Allergy and Clinical Immunology, 2019, 144 (2), pp.524-535.e8. ⟨10.1016/j.jaci.2018.10.064⟩
Article dans une revue hal-02284256v1

IgE in the pathophysiology and therapy of food allergy

Marine Michelet , Bianca Balbino , Laurent Guilleminault , Laurent Reber
European Journal of Immunology, 2021, 51 (3), pp.531-543. ⟨10.1002/eji.202048833⟩
Article dans une revue hal-03779488v1
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High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

Annabelle Gérard , Adam Woolfe , Guillaume Mottet , Marcel Reichen , Carlos Castrillón , et al.
Nature Biotechnology, 2020, 38, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Article dans une revue pasteur-02505776v1
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The Quantitative Assessment of the Secreted IgG Repertoire after Recall to Evaluate the Quality of Immunizations

Klaus Eyer , Carlos Castrillon , Guilhem Chenon , Jérôme Bibette , Pierre Bruhns , et al.
Journal of Immunology, 2020, 205 (4), pp.1176-1184. ⟨10.4049/jimmunol.2000112⟩
Article dans une revue hal-03054257v1
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CD32A-expressing platelets determine the severity of experimental anaphylaxis.

Héloïse Beutier , Béatrice Hechler , Ophélie Godon , Yu Wang , Caitlin M. Gillis , et al.
Science Immunology, 2018, 3 (22), ⟨10.1126/sciimmunol.aan5997⟩
Article dans une revue pasteur-01928557v1